Expression of Beclin-1, an Autophagic Gene, in Hepatocellular Carcinoma Associated with Clinical Pathological and Prognostic
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منابع مشابه
Association of autophagy defect with a malignant phenotype and poor prognosis of hepatocellular carcinoma.
Hepatocellular carcinoma (HCC) is an aggressive cancer with a poor prognosis. The role of autophagy and the prognostic value of autophagic genes are largely unknown in HCC. Here, we showed decreased expression of autophagic genes and their corresponding autophagic activity and increased expression of the antiapoptotic gene Bcl-xL in HCC cell lines compared with a normal hepatic cell line. We al...
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